The MOUSE ANTI HUMAN CD14:RPE Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD14. This antibody recognizes Human antigen. The MOUSE ANTI HUMAN CD14:RPE Antibody has been validated for the following applications: Flow Cytometry.
Description
Mouse anti Human CD14 antibody, clone UCHM1 recognizes a cell surface antigen of 55 kD, known as CD14.The CD14 molecule is found predominantly on monocytes and macrophages in flow cytometry, it is less strongly expressed on granulocytes, and is absent from stem cells and myeloid cells of very early differentiation states. In immunohistology the CD14 molecule is found to be present on Langerhans cells, follicular dendritic cells, histiocytes and high endothelial venules. Antibodies to the CD14 molecule are known to induce oxidative burst formation. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative (Hogg et al. 1984). UCHM1 also reacts with Kupffer cells and sinus lining cells on the liver